Anticoccidial Activity of Amprosul (Agrar®) on Sporulation of Eimeria maxima Oocysts

Bosede A. Ogwurike; Akwashiki Ombugadu; Njila Livinus Hasley; James I. Maikenti; Victor A. Adejoh; Samson A. Da’an; Sylvester A. Attah; Joseph O. Ayim; Bukola A. Ajide; Oluwamuyiwa O. Baiyewu; Innocent A. Polycarp.

Transactions on Science and Technology, 9(1), 21 - 25.

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Sporulation is necessary if the life cycle of an Eimeria oocyst is to continue. Therefore, the study on anticoccidial activity of Amprosul (Agrar®) on sporulation of Eimeria maxima oocysts was investigated. The sporulation rates of oocysts of Eimeria maxima isolated from broiler chickens infected but not medicated and those infected and medicated with 0.5g and 1g of Amprosul (Agrar ®)/l of water were studied at room temperature. Normal oocysts, N (isolated from infected, unmedicated birds) sporulated faster and in greater numbers than principal oocysts P1 and P2 isolated from infected, medicated chickens (with 0.5g and 1g of Amprosul/l of water respectively). Oocysts isolated from chickens that received the higher dose of the drug sporulated slower and in lower numbers than those isolated from chickens treated with the lower dose. Average sporulation rate in relation to the treatments at 36, 48 and 72 hours respectively showed a very high significant difference (P < 0.001) while no significant variation (P > 0.05) was observed across treatments at the 96th hour. In conclusion, this study shows that Amprosul (Agrar®) drug can inhibit the sporulation of chicken Eimeria oocysts which will help in the termination of coccidiosis breaks in poultry houses resulting to huge economic gain.

KEYWORDS: Chickens, Eimeria maxima, Oocysts, Sporulation, Amprosul (Agrar ®).

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