Evaluation of the Phytochemical, Antioxidant and Anti-microbial Activities obtained from the Methanolic Leaf Extracts of Melia dubia Cav.

B. Dinesh, P. Mahesh, M. Shanthala, V. Shalini, R. Sindhu, K. N. Viji, Somashekara Rajashekara

Melia dubia Cav. is a native species of tree to India and a sub canopy tree species naturally found in the tropical moist deciduous and semi-evergreen forest of south Indian region. The leaves of M. dubia samples collected from the Chikkaballapura (MDL1) and Bengaluru (MDL2) region were screened for the detection of phytochemical contents and for the determination of antioxidants such as ABTS Radical Scavenging Assay, Total Reducing Power Assay, Hydrogen peroxide radical scavenging activity and their evaluation of anti-microbial activity. Phytochemical analysis of leaf extract of M. dubia revealed that the presence of significant plant secondary metabolites contributes to its anti-microbial and antioxidant activity. Thus, M. dubia can be used as a potential source for development of potential anti-microbial drug of botanical origin comparable to synthetic pesticides. Phytochemicals contents present in the leaf extracts are capable of rendering health benefits, thereby demonstrating that M. dubia can be a probable medicinal plant for human mankind.

KEYWORDS: Antioxidants; Anti-microbial activity; Phytochemicals; Secondary metabolites



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