Abstract and References
Transactions on Science and Technology Vol. 4, No. 3-3, 360 - 365, 2017

Phytochemical Analysis and Antioxidant Activity of Ficus lepicarpa Leaves from Sabah, Malaysia

Senty Vun-Sang, Teoh Peik-Lin, Kenneth Francis Rodriques, Mohammad Iqbal

ABSTRACT
Ficus lepicarpa belongs to family Moraceae and commonly known as ‘Saraca fig’. It has been used by local people as vegetable dish, as a tonic and to treat aliments such as fever and ringworm. The present study was aimed at evaluating the phytochemical constituents and antioxidant activity of methanol extract of F. lepicarpa leaves. The antioxidant activity of F. lepicarpa leaves extracts were estimated using FRAP assay (ferric reducing antioxidant potential) method. The test of phytochemical screening showed the presence of flavonoids, saponins, steroids, phytosterols, and absence of alkaloids, tannins, phenols, anthraquinones and triterpenoids. The result obtained from this study provides information that F. lepicarpa has antioxidant activity and possesses the potential to be used to treat or prevent degenerative diseases where oxidative stress is implicated. Further studies are in progress to evaluate the in vivo potential of F. lepicarpa in animal model of carbon tetrachloride mediated oxidative tissue injury.

KEYWORDS: Phytochemical constituents, Antioxidant activity, Ficus lepicarpa, Moraceae, Leaves Extract

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REFERENCES

Ahmad, F. B. & Holdsworth, D.K. (1995). Traditional Medicinal Plants of Sabah, Malaysia – Part III. The Rungus People of Kudat. International Journal of Pharmacognosy, 33(3), 262 – 264.

Ahmad, F. B. & Holdsworth, D.K. (2003). Medical Plants of Sabah, East Malaysia – Part I. Pharmaceutical Biology, 41(5), 340 – 346.

Azlim Almey, A.A., Ahmed Jalal Khan, C., Syed Zahir, I., Mustapha Suleiman, K., Aisyah, M.R. & Kamarul Rahim, K. (2010). Total Phenolic Content and Primary Antioxidant Activity of Methanolic and Ethanolic Extracts of Aromatic Plants’ Leaves. International Food Research Journal, 17, 1077 – 1084.

Chan, E. W. C., Lim, Y.Y., & Mohammed Omar. (2007). Antioxidant and Antibacterial Activity of Leaves of Etlingera Species (Zingiberaceae) in Peninsular Malaysia. Food Chemistry, 104, 1586 – 1593.

Corner, E. J. H. (1975). New Taxa of Ficus (Moraceae) 2. Blumea, 22, 299 – 309.

Faridah Hanum, I. & Hamzah, N. (1999). The use of medicinal plant species by the Temuan Tribe of Ayer Hitam Forest, Selangor, Peninsular Malaysia. Journal of Tropical Agriculture Science, 22(2), 85 – 94.

Firdouse, S. & Alam, P. (2011). Phytochemical investigation of extract of Amorphophallus campanulatus tubers. International Journal of Phytomedicine, 3, 32 – 35.

Grison-Pige, L., Hossaert-McKey M., Greeff, J. M. & Bessie`re J. M. (2002). Fig volatile compounds—a first comparative study. Phytochemistry, 61, 61 – 71.

Harborne, J. B. (1998). Phytochemical Methods. A Guide to Modern Techniques of Plant Analysis (3rd edition). New York: Chapman and Hall.

Hodzic, Z., Pasalic, H., Memisevic, A., Scrabovic, M., Saletovic, M. & Poljakovic, M. (2009). The Influence of Total Phenols Content on Antioxidant Capacity in the Whole Grain Extracts. European Journal of Scientific Research, 28, 471 – 477.

Hossain, M. A., AL-Raqmi, K. A. S., AL-Mijizy, Z. H., Weli, A. M. & Al-Riyami, Q. (2013). Study of Total Phenol, Flavonoids Contents and Phytochemical Screening of Various Leaves Crude Extracts of Locally Grown Thymus vulgaris. Asian Pacific Journal of Tropical Biomedicine, 3(9), 705 – 710.

Jansen, P. C. M., Jukema, J., Oyen, L. P. A. & van Lingen, T. G. (2016). Plant Resources of South-East Asia (PROSEA): Ficus lepicarpa. (http://uses.plantnet­project.org/e/index.php?title=Ficus_lepicarpa_(PROSEA)&oldid=202727). Accessed on 28 July 2016.

Jantan, I., Jumuddin, F. A., Saputri, F. C. & Rahman, K. (2014). Inhibitory effects of the extracts of Garcinia species on human low density lipoprotein peroxidation and platelet aggregation in relation to their total phenolic contents. Journal of Medicinal Plants Research, 5(13), 2699 – 2709.

Kulip, J. (2003). An enthnobotanical survey of medicinal and other useful plants of Muruts in Sabah, Malaysia. Telopea, 10, 81 – 98.

Milow, P., Sorayya Bibi Malek, Edo, J. & Ong, H. C. (2014). Malaysian Species of Plants with EdibleFruits or Seeds and Their Valuation. International Journal of Fruit Science, 14(1), 1 – 27.

Philip, D., Kaleena, P. K., Valivittan, K. & Girish Kumar, C. P. (2011). Phytochemical Screening and Antimicrobial Activity of Sansevieria roxburghiana Schult. and Schult. F. Middle-East Journal of Scientific Research, 10(4), 512 – 518.

Rahim, Z. H. A. & Khan, H. B. S. G. (2006). Comparative studies on the effect of crude aqueous (CA) and solvent (CM) extracts of clove on the carcinogenic properties of Streptococcus mutants. Journal of Oral Science, 48(3), 117 – 123.

Suhaj, M. (2006). Spice Antioxidants Isolation and Their Antiradical Activity: A Review. Journal of Food Composition and Analysis, 19, 531 – 537.

Ugochukwu, S. C., Uche I., A. & Ifeanyi, O. (2013). Preliminary Phytochemical Screening of Different Solvent Extracts of Stem Bark and Roots of Dennetia tripetala G. Baker. Asian Journal of Plant Science and Research, 3(3), 10 – 13.

Velioglu, Y. S., Mazza, G., Gao, L. & Oomah, B. D. (1998). Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products. Journal of Agricultural Food and Chemistry, 46, 4113 – 4117.

Vimalkumar, C. S., Hosagaudar, V. B., Suja, S. R., Vilash, V., Krishnakumar, N. M. & Latha, P. G. (2014). Comparative Preliminary Phytochemical Analysis of Ethanolic Extracts of Leaves of Olea dioica Roxb., Infected with the Rust Fungus Zaghouania oleae (E.J. Butler) Cummins and Non-infected Plants. Journal of Pharmacognosy and Phytochemistry, 3(4), 69 – 72.

Zou, Y. P., Lu, Y. H. & Wei, D. Z. (2004). Antioxidant Activity of Flavonoid-rich Extract of Hypericum perforatum L. In-vitro. Journal of Agriculture and Food Chemistry, 52, 5032 – 5039.